Principal Machine Learning Operations Engineer is open at Definitive Healthcare, US in Framingham, MA. The posting gives a salary of $158K - $294K. Posted on Sep 18, 2026, and still on Definitive Healthcare, US’s careers page when we last checked, on Nov 14, 2026.
About the role
We are seeking a hands-on Principal MLOps Engineer & Functional Lead to architect, build, and scale our next-generation Machine Learning and Generative AI infrastructure. In this role, you will design a unified, automated, and secure AI ecosystem capable of training and deploying both traditional predictive models and advanced Generative/Agentic AI systems at enterprise scale. As the Functional Lead, you will drive…
The opening lines of the posting. The rest is on Definitive Healthcare, US’s careers page.
Hiring at Definitive Healthcare, US
Definitive Healthcare, US has 28 open roles right now, 23 of them remote. Most are in Sales & Business Development, Data & Research and Education & Training. The median advertised salary across its roles with a published range is $139K. See all its roles

